Cell, Gene and Therapy Journal

Peer-reviewed multi-disciplinary and Open Access journal accepts scientifically rigorous research, regardless of novelty

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Efficacy of zinc sulfate on common cold in children aged 1-5 years admitted at Javaheri hospital in Tehran

Hematyar Masoumeh*1, Nikta Basim2
1 Associate Professor of Pediatrics, Islamic Azad University Tehran Medical Science
2 General Practitioner, Islamic Azad University Tehran Medical Science

Introduction: Common cold is the most common acute upper respiratory tract disease in children. The efficacy of vitamins and minerals for duration, symptoms and complications of common cold has been evaluated in several studies. This study was performed to determine the efficacy of zinc sulfate on common cold in children aged 1-5 years attending to Javaheri hospital in 2012-2013.
Materials and Methods: In this clinical trial study, 112 children with common cold aged 1 to 5 years who were admitted at Javaheri hospital in 2012-2013 were enrolled. They were randomly assigned to receive either conventional treatment including Acetaminophen, Pediatric cold and nasal drop as control group or the aforementioned drugs plus zinc sulfate 1 mg/kg/day for 5 days. The duration of symptoms and rate of complications were compared between two groups.
Results: The results revealed that the duration of disease was significantly shorter in case group (P = 0.033). Also the frequency of nasal discharge, sneezing, cough and sinusitis was significantly less in case group (P<0.05).
Conclusion: In summary, it can be concluded that zinc sulfate is effective in reducing the symptoms, duration and complications of common cold in children aged from 1-5 years within 24 hours of the disease onset.

Keywords : Zinc sulfate, Common cold, Children, Complications


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